Matthew Nicholas

Brenner, S., F. Berger, L. Rao, M. P. Nicholas, and A. Gennerich. Force production of human cytoplasmic dynein is limited by its processivity. 2020. Sci. Adv. 6:eaaz4295. PDF

Rao, L., F. Berger, M. P. Nicholas, and A. Gennerich. Molecular mechanism of cytoplasmic dynein tension sensing. 2019. Nat. Commun. 10:3332. PDF

Nicholas, M. P., F. Berger, L. Rao, S. Brenner, C. Cho, and A. Gennerich. Cytoplasmic dynein regulates its attachment to microtubules via nucleotide state-switched mechanosensing at multiple AAA domains. 2015. Proc. Natl. Acad. Sci. USA 112:6371–6376. PDF

Nicholas, M. P.*, P. Hook*, S. Brenner, C. Lazar, R. B. Vallee#, and A. Gennerich#. Control of cytoplasmic dynein force production and processivity by its C-terminal domain. 2015. Nat. Commun. 6:6206 (*: co-first authors; #: co-corresponding authors). PDF

Nicholas, M. P., L. Rao, and A. Gennerich. Covalent immobilization of microtubules on glass surfaces for molecular motor force measurements and other single-molecule assays. 2014. Methods Mol. Biol. 1136:137–169. PDF

Nicholas, M. P., L. Rao, and A. Gennerich. An improved optical tweezers assay for measuring the force generation of single kinesin molecules. 2014. Methods Mol. Biol. 1136:171–246. PDF

Rao, L.*, E. M. Romes*, M. P. Nicholas, S. Brenner, T. Ashutosh, A. Gennerich#, and K. C. Slep#. The yeast dynein Dyn2–Pac11 complex is a dynein dimerization/processivity factor: structural and single-molecule characterization. 2013. Mol. Biol. Cell 24:2362–2377 (*: co-first authors; #: co-corresponding authors). PDF

Nicholas, M. P., E. Ertan, F. Fabien, C. David, and G. Ranajeet. Nuclear spin relaxation in isotropic and anisotropic media. 2010. Prog. Nucl. Magn. Reson. Spectrosc. 57:111–158. PDF